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Image Search Results
Journal: Free radical biology & medicine
Article Title: In vivo vascular rarefaction and hypertension induced by dexamethasone are related to phosphatase PTP1B activation not endothelial metabolic changes
doi: 10.1016/j.freeradbiomed.2020.01.012
Figure Lengend Snippet: (A) Dex (100 µM, 24 h) did not modify VEGF-induced Akt and eNOS phosphorylation. Basal levels of Akt and eNOS were confirmed in duplicate experiments (B) PTP1B inhibitor (KY226), glucocorticoid receptor inhibitor (RU486), and Dex (100 µM, 24 h) enhance VEGF-induced eNOS phosphorylation. Values represent the mean±SEM from 3 independent replicates. +p<0.05 VEGF stimulation.
Article Snippet: Dexamethasone sodium phosphate (Decadron®) was obtained from Aché Laboratory, (Guarulhos, SP, Brazil),
Techniques: Phospho-proteomics